Which side effects can occur when Ativan is administered to older adults?

Ativan, or lorazepam, is a benzodiazepine used primarily for anxiety and sedation. In older adults, its use can lead to heightened sensitivity to the medication's effects, making side effects more pronounced than in younger populations. Among the potential side effects, agitation and delirium are particularly concerning.

This demographic may experience confusion, disorientation, and a state of heightened agitation as a result of receiving Ativan. These effects are primarily due to the central nervous system depression that benzodiazepines exert, which can disturb cognitive function and exacerbate underlying health issues common in older adults, such as dementia or other forms of cognitive impairment.

Furthermore, the pharmacokinetics of Ativan, including its metabolism and clearance, can be altered in older patients, contributing to a greater risk of these adverse reactions. As such, monitoring for signs of agitation and delirium is critical when administering Ativan to older adults, making this side effect a significant concern compared to the other listed options.